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BIH at Charité Newsletter
No 6/2021 | July/August Issue

Dear Readers,

What a summer it’s been! Torrential rain and flooding in the north, relentless heat and fires in the south, plus a resurgent pandemic and, last but not least, the mounting tensions in the run up to the Berlin and national elections with still uncertain prospects for an issue close to our hearts, research. We very much hope that in any case you managed to have a safe, enjoyable and relaxing holiday season, and that you have now returned to your office desk, lab bench or hospital ward in good health and good spirits. Quite a bit has happened at the BIH in July and August: We have welcomed new colleagues, published interesting research results and started to create a digital monument to Berlin’s female scientists through the project Hauptstadt der Wissenschaftler*innen, or Capital of Women in Science. Read for yourself!

With kind regards,
Your BIH Board of Directors
Christopher Baum and
Johannes Voß-Lünemann (interim)
 

Corona/COVID-19: Activities of the BIH

CovApp on Smartphone

Even Vaccinated Benefit From New and Improved CovApp 2.0

As of now, a version of the CovApp adapted to the current pandemic situation is freely available on the Internet. CovApp 2.0 not only answers questions about rapid antigen or PCR tests, but also provides advice for vaccinated and recovered people – for example, about symptoms or positive test results despite their assumed immunity. The app helps identify at-risk individuals and those who could benefit from special – and potentially life-saving – therapies. The updated version of CovApp was developed by an interdisciplinary team from the BIH, Charité and the Robert Koch Institute led by the spokesperson of the Digital Clinician Scientist Program, Dr. Alexander Thieme, and can be downloaded free onto a mobile phone.

Read the press release
Link to CovApp
Hand holding smartphone with BärCODE app on it

homeDX – First Virtual Corona Test Center With Bärcode

In May, homeDX was launched as the first virtual rapid test center in Berlin-Mitte. With the certificate of homeDX, which is equipped with the tamper-proof BärCODE, users got exclusive access to Berlin restaurants. Now the project is being extended to the whole of Berlin.

Read more
 

News From the BIH

BIH at Charité Newsletter

European Recognition for Digital Brain Research

EBRAINS is a digital research infrastructure, created by the EU-funded Human Brain Project, that aims to digitally explore and decode the human brain. Now, after a highly competitive selection process, EBRAINS has been included in the 2021 Roadmap of the European Strategy Forum on Research Infrastructures (ESFRI), laying the foundation for long-term operation over the next 10 to 20 years. Professor Petra Ritter is also involved through the Brain Simulation Section at the BIH and the Department of Neurology with Experimental Neurology at Charité. She runs The Virtual Brain, an open-source platform for constructing and simulating personalized brain network models.

Read the press release
BIH at Charité Newsletter

New DFG Research Unit Approved

Lower back pain is one of the most common ailments of the musculoskeletal system. A newly approved DFG Research Unit aims to gain new insights into the development of back pain in order to improve diagnosis and therapy. The group's spokesperson is Professor Hendrik Schmidt from the Julius Wolff Institute of Biomechanics and Musculoskeletal Regeneration at the BIH. Individuals aged 18 to 64 with and without back pain are being sought for the study. The study is expected to start on 1 January 2022.

Read the press release
Information about the study
BIH at Charité Newsletter

Four Times as Much Information per Cell

Scientists from the BIH and the MDC have teamed up with U.S. and Japanese researchers to take single-cell analysis to a new level. They combined methods for determining mRNA levels and DNA accessibility with those used for detecting proteins and mutations in mitochondrial DNA, thus allowing them to simultaneously profile all this information from thousands of individual cells. The researchers have now published their findings in the journal Nature Biotechnology. Leif S. Ludwig, head of the Emmy Noether Junior Research Group "Stem Cell Dynamics and Mitochondrial Genomics" at the BIH and theMDC, is one of the lead authors of the now published paper.

Read the press release
Read the publication
Goup image of the cosortium partner of the project HerzCheck and invited guests

HerzCheck – Official Start in Templin

On 1 July 2021, the Innovation Fund project "HerzCheck" was officially opened in Templin together with Brandenburg's Minister of Health and the CEO of AOK Nordost. With the help of innovative mobile cardio-MRI diagnostics and telemedical support, high-risk patients in rural regions can take advantage of an individualized form of care for the early detection of heart failure. The project "HerzCheck" is the first cooperation project between the German Heart Center Berlin (DHZB) and the Charité BIH Clinical Study Center.

Read more (only in German)
BIH at Charité Newsletter

Wissensstadt Berlin 2021

Since the end of June, more than 100 events on health, climate and coexistence have been taking place in the "Wissensstadt Berlin" - both on site and digitally. The BIH was also involved with several exciting events.

Read more / Program details
 

Awards

Anton Henssen Receives Yound Investigator Berlin Science Award from Michael Müller

Young Investigator Berlin Science Award for Anton Henssen

Dr. Anton Henssen, a scientist and physician at the ECRC, has received the Young Investigator Award of the 2020 Berliner Wissenschaftspreis for his cutting-edge research into childhood cancers. Henssen has been a member of the BIH Charité (Junior) Clinician Scientist Program since 2016. The award of 10.000 euros was presented by the Governing Mayor of Berlin Michael Müller at a ceremony on July 22 in front of the Rotes Rathaus together with Professor Christian Drosten who was awarded the Berliner Wissenschaftspreis.

Read the press release
BIH at Charité Newsletter
Portrait Carl Weidinger

Carl Weidinger Receives DACED Future Award

The German work group for Inflammatory Bowel Diseases (DACED) awarded the DACED Future Prize for the twelfth time in July 2021. The BIH Charité Clinician Scientist Dr. med. Carl Weidinger from the Medical Clinic for Gastroenterology, Infectiology and Rheumatology (Charité Campus Benjamin Franklin) was awarded the Future Prize of the German work group for Inflammatory Bowel Diseases (DACED) for his work on the significance of fatty tissue in Crohn's disease. The prize is endowed with 7.500 euros. Another award went to PD Dr. med. Konrad Aden from the University Medical Center Schleswig-Holstein.

Read more (only in German)
 

Personalia

Logo BIH at Charité

BIH Governing Board Constituted

On 24 June 2021 the constituent meeting of the BIH Governing Board took place. Chair of the Governing Board is the representative of the Federal Government, State Secretary at the Federal Ministry of Education and Research (BMBF), Christian Luft, his deputy is Steffen Krach, State Secretary for Science and Research of the State of Berlin. External experts are Professor Blanche Schwappach-Pignataro, Dean of the University of Hamburg-Eppendorf, Professor Monika Jungbauer-Gans, Scientific Director of the German Center for Higher Education Research and Science Studies, Annette Schavan, former Federal Minister and Dr. Christian Rommel, Head of Research and Development of the Pharmaceuticals Division of BAYER AG.

Read more
BIH at Charité Newsletter

New Members of the Scientific Advisory Board of BIH

The Governing Board has appointed Professor Aviv Regev, Head of Genetech Research and Early Development and Professor David A. Williams, Leland Fikes Professor of Pediatrics at Harvard Medical School, Chief of Hematology/Oncology, Senior Vice President and Chief Scientific Officer at Boston Children's Hospital as new members of the BIH Scientific Advisory Board, effective 1 July 2021. Both fill previously vacant positions. Professor David Moher, Senior Scientist at Ottawa Research Hospital, and Professor Claudia Schmidtke, Member of the German Bundestag, Commissioner for Patient Affairs of the Federal Government were appointed as of 1 October 2021.

Read more
Portraits of Kati Jegzentis and Ljudmila Borisenko

The New BIH Staff Council Starts Working

With the constituent meeting on 22 July 2021, the Staff Council, elected at the end of June 2021, began its work. The elected board consists of Kati Jegzentis (Coordinator Clinical Research Unit, Chair of the Staff Council) and Ljudmila Borisenko (Team Leader Areas & Onboarding, BIH Office, Vice Chair). The Staff Council meets weekly to discuss upcoming personnel issues and also your issues as an employee of BIH. Please bring your problems, complaints and suggestions to the table. Please contact personalrat-bih@bih-charite.de.

Read more
Portraits of Thomas Gazlig and Claudia Keil-Dieckmann

New Management Structure at Charité BIH Innovation

The previous acting head of Charité BIH Innovation, the joint technology transfer of BIH and Charité, Thomas Gazlig, will be responsible for the business area as Director in the future and will hand over the management of the Business Division Research at Charité. Gazlig has already been acting director of Charité BIH Innovation for two years. He has held various management positions at Charité since 2012 and previously worked in the management at the Helmholtz Association of German Research Centers. New in the Charité BIH Innovation management team is Dr. Claudia Keil-Dieckmann. She has taken over as Head of the Law, Patents, Licenses team and is also Deputy Director. The biologist is an experienced scientist and research manager with many years of extensive expertise in technology transfer and her own start-up experience.

Read more about Charité BIH Innovation
Portrait Janine Altmüller

Janine Altmüller Is New Head of the Genomics Platform

Dr. Janine Altmüller’s goal is to raise the profile of genomics research in Berlin. Since 1 July 2021 she has headed the BIH and MDC’s joint Genomics Platform, providing support to Berlin researchers and honing new methods and technologies. Unlike genetics, which is the study of single genes, genomics studies the entire genome.

Read the press release
Further information
 

News From the Staff Office Equal Opportunities

Portraitt Louise Pilote

Incorporating Gender-Related Variables in Clinical Research

Dr. Louise Pilote, who was awarded the BIH Excellence Award in 2017 for her research about possible effects of gender differences when it comes to medical issues such as cardiovascular disease, together with colleagues published an information in the method series of the Canadian Institutes of Health about how to incorporate Gender-related variables in clinical research. Interested researchers can learn more about the differences between sex and gender related variables, why the consideration of gender might be important and which methods can be used.

Read more
Screenshot online seminar edit-a-thon

Berlin Edit-a-thon – Capital of Women Scientists

At the end of July 2021, the joint project of BIH and the Berlin Senate Chancellery was successfully launched as part of Wissenstadt Berlin. Together with interested citizens of the city, the project aims to give more visibility to Berlin's female scientists, past and present. On 28 July the project kicked off with a Wikipedia Edit-a-thon in which about 35 people participated online. The goal is to write Wikipedia entries by Berlin women scientists in the coming weeks, thus giving women greater visibility online. Those interested are welcome to participate online.

Read more (only in German)
 

News From the BIH Biomedical Innovation Academy (BIA)

Front page of the Bibliometrics Report of the (Junior) Clinician Scientist Program Evaluation

Scientific Output of the (Junior) Clinician Scientists

As part of the evaluation of the BIH Charité (Junior) Clinician Scientist Program, the BIA cooperated with the BIH QUEST Center. The scientific output of the program was analyzed by Dr. Nico Riedel from BIH QUEST using a wide variety of bibliometric metrics. The bibliometrics report is now available online.

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BIH at Charité Newsletter

Marcus Czabanka Appointed Clinical Director in Frankfurt a.M.

The alumnus of the BIH Charité Clinician Scientist Pilot Program, Professor Marcus Czabanka, MD, previously Deputy Director of the Neurosurgical Clinic at Charité, has been appointed Director of the Clinic for Neurosurgery at the University Hospital of the Goethe University Frankfurt. Congratulations!

Read more (only in German)
BIH at Charité Newsletter
Portrait Andreas Horn

Andreas Horn Receives Professorship at Harvard

The alumnus of the BIH Charité Junior Clinician Scientist Program and participant of the Clinician Scientist "Excellence Track" Dr. med. PhD Andreas Horn was appointed professor in Harvard. He will hold appointments in the Department of Neurology and Psychiatry and in the Departments of Neurology and Neurosurgery. We congratulate!

Read more
BIH at Charité Newsletter

Now Online: All Sessions of the Memorial Symposium

On 28 + 29 May 2021, the international memorial symposium in honour of Professor Duška Dragun and on the occasion of the tenth anniversary of the BIH Charité Clinician Scientist Program was held. All contents of the "Memorial Session" and on the "Science Policy Session" as well as on the scientific sessions are now online.

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Link to the sessions
 

News From the BIH QUEST Center

Logo BIH QUEST Center and claim Stakeholder Engagement

BIH QUEST Grant for Patient & Stakeholder Engagement

The BIH QUEST Grant for Patient & Stakeholder Engagement was first published in 2021. With this call, we want to foster the active engagement of patients and other stakeholders (e.g., relatives) especially in the planning phase (e.g., protocol development) of a study. Four projects from Charité were selected for funding. We warmly congratulate all successful applicants!

Read more
 

News From Charité BIH Innovation

BIH at Charité Newsletter

Charité BIH Innovation – New Name for the Technology Transfer

With the new name "Charité BIH Innovation", the technology transfer of Charité and BIH makes it clear that it is a joint service unit. Since 2016, employees of BIH and Charité have been successfully working together under one roof and one management. However, the previous name BIH Innovations has repeatedly led to irritation, as the connection to Charité was not immediately obvious. After the integration of BIH into Charité, Charité BIH Innovation is a joint business unit of the faculty and the BIH and has two separate budgets and employees in both departments.

Read more about Charité BIH Innovation
BIH at Charité Newsletter

Joint Exploitation Regulation for Charité and BIH

With a joint exploitation regulation, Charité and the BIH for the first time regulate all questions of use, protection and exploitation of work results in an overarching manner. The exploitation regulation was developed in an extensive coordination and discussion process with the federal government, the state and many committees of Charité and BIH. The exploitation regulation also lays the foundation for a transfer fund: 20 percent of future income from work results will be used as an innovation lump sum to form a transfer fund, which will be used to finance future development projects.

Read more (only in German)
 
BIH at Charité Newsletter

AI in the ICU: X-Cardiac Gets Approval for X-C-Bleeding

x-cardiac GmbH has been certified as a medical device manufacturer in the EU while at the same time receiving market authorization for its first medical device x-c-bleeding. The AI-based software can quickly predict the risk of postoperative bleeding in patients. Specialists at the German Heart Center Berlin (DHZB) around Professor Alexander Meyer developed the software and benefited from various support programs of the Berlin Institute of Health at Charité (BIH).

Read the press release
BIH at Charité Newsletter

Nephrolytix Wins Science4Life Venture Cup

On 28 June 2021, Nephrolytix by Professor Markus van der Giet, Charité - Universitätsmedizin Berlin, was awarded  as the winner of the Science4Life Venture Cup for Life Sciences and Chemistry after their pitch in front of a jury of experts, making it one of the most innovative start-ups 2021. The project has been funded in the BIH Digital Health Accelerator program since August 2019. We are delighted with Professor van der Giet and his team. Congratulations!

Read more
 

New BIH Podcast Episode

How Did The Coronavirus Influence Research?

In our 32nd episode of the BIH Podcast Series John Ioannidis, meta researcher at Stanford and the BIH, speeks about how the Corona pandemic affected the integrity, transparency and sustainability of research results.

Listen to the podcast
BIH at Charité Newsletter

BIH Podcast Series "Turning Research Into Health"

You can find more interesting podcasts on our website (only in German).

BIH Podcast Series
 

Open Calls

Logo BIH Regeneration

BIH Charité RegTherapies Incubator Call 2022

The funding is intended as seed financing to reach phase I/IIa clinical trials for Advanced Therapies and boost the translational chain, serving as basis to apply for substantial third-party funds. Projects should have a clear clinical or technical translational pathway and be innovative in nature. Projects must also be interdisciplinary, including a minimum of 2 BIH principal investigators (PI) from different fields or disciplines and a Charité clinical partner (unless covered by a BIH PI). Applications must be written in English and received by 23:59 h on 29 August 2021. 

Read more
Logo Stiftung Charié

Max Rubner Award 2022 – The Innovation Award for Trailblazers

The Max Rubner Award supports the implementation of innovative ideas at Charité. The prize money shall act as an initial funding for intrapreneurs, i.e. individuals or teams addressing challenges within the Charité with an entrepreneurial approach by developing new services, products or initiatives. All professional groups as well as students of Charité can participate. Deadline is 1 September 2021.

Read more
BIH at Charité Newsletter
Logo BIH Academy

Current Call For Applications for the Clinician Scientist Programs

On 2 September 2021, the calls for applications for the (Junior) (Digital) Clinician Scientist Program will be published. The various provide research-based physicians at different career levels a structured residency training with “protected time” for research. Deadline for all calls for applications is 30 September 2021.

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Quality-Promoting Aspects in Medicine and Biomedicine

We would like to draw your attention to the fact that the DFG Working Group "Quality in Clinical Research" of the Permanent Senate Commission on Basic Questions in Clinical Research has published a guideline that helps to systematically describe quality-promoting aspects in funding proposals and thus to better take them into account in review and evaluation.

Read more / To the guide (only in German)
 

New Faces at the BIH

Business Division Science Management

Dr. Mara Hartung

Dr. Mara Hartung joined the Science Management Team as Scientific Coordinator in the beginning of April 2021. Here she is responsible for the Translation-Hub Clinical Translation as well as the development of the project Case Analysis and Decision Support (CADS). She holds a PhD in natural sciences and has previously worked as a project manager in various positions both in academic and pharmaceutical sectors. 
Portrait Mara Hartung

Charité BIH Innovation / SPARK-BIH

Nadine Neef

Nadine Neef joined Charité BIH Innovation at the beginning of April 2021 as Administrator for Patents and Licenses. Her core tasks include administrative support for contracts and accounting as well as budget planning and monitoring.
Portrait Nadine Neef
BIH at Charité Newsletter

Katharina Clausnitzer

Katharina Clausnitzer has been working at the BIH as a student assistant in the SPARK-BIH team since April 2021. She is currently studying biotechnology in her second master's semester at the Beuth University of Applied Sciences and supports the SPARK team mainly in organizational tasks and graphic design.
Portrait Katharina Clausnitzer
 
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